Single-cell omics is a rapidly growing new field that provides many advantages over traditional 'bulk' tissue profiling methods, such as the ability to resolve intratissue heterogeneity in cell types, profile the disease microenvironments, and study rare subpopulations. Over the last several years, single-cell genomic and transcriptome methods have had major impact on many areas of biomedical research. In addition to single cell genomic and transcriptome method, additional omics technologies, such as chromatin profiling, DNA methylation, and proteomics, are under rapid development. Together these single cell omics technologies are becoming essential tools that are revolutionizing many diverse fields of biomedical research. However, the development of single cell omics technology requires multidisciplinary teams with expertise in bioengineering, chemistry, biomedical science, and computational biology. In addition, most single cell omics methods are difficult to perform and restricted to expert laboratories that have specialized skills and equipment. Furthermore, the resulting large-scale datasets are challenging to analyze and requires expertise in bioinformatics, computational biology, statistics, and data science. Therefore, this is a significant gap and opportunity in both technology development and dissemination. The GCC single cell omics cluster aims at leveraging the expertise at different institutions and maximize the interdisciplinary synergy of the group.
Professor, Associate Department Chair, Director of Graduate Studies, Chemical and Biomolecular Engineering, Associate Professor, Materials Science and NanoEngineering, Rice University
Professor & Director, John S. Dunn Chair in Disease Prevention, Center for Epigenetics & Disease Prevention, Institute of Biosciences and Technology -TAMHSC
Chair, Robert and Janice McNair Endowed Chair and Professor, Molecular and Human Genetics, Professor, Integrative Molecular and Biomedical Sciences, Developmental Biology, Translational Biology & Molecular Medicine, Baylor College of Medicine
Director, Center for Drug Discovery, Stuart A. Wallace Chair and Professor, Robert L. Moody, Sr. Chair, Pathology & Immunology, Baylor College of Medicine
Professor & Director, Center for Precision Environmental Health, Departments of Molecular & Cellular Biology, Medicine, Genetics, Baylor College of Medicine
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