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Faculty Profile Last Modified Time: 02:11:43 PM Fri, 17 Apr 2020   Contact Information Richard Willson Associated Profiles  Professor, Biology and Biochemistry, University of Houston   Engineering Bldg 1, Room No.: 228    willson@uh.edu     713-743-4308    Web Link    Lab Webpage    PCR, Gel Electrophoresis, DNA, Electrophoresis, Cloning, Cancer Biology, RNA, DNA Sequencing, Molecular Genetics, Sequencing, Genomics, Proteins, Molecular Cloning, Bioinformatics and Computational Biology, Genetic Engineering, Bacteriophage, Aptamers    Associated Profiles Research and Expertise Affiliations Appointments  Research and Expertise Research Interests   Richard Willson's laboratory works on biomolecular recognition, and its applications in separations and molecular diagnostics. Professor Willson is interested in the structural determinants of molecular recognition in complexes of proteins with recognition agents such as monoclonal antibodies and aptamers. The primary techniques used in the laboratory are expression, mutagenesis, fluorescence anisotropy (kinetics), and titration calorimetry. Topics of current interest include the recognition of hen egg lysozyme by a 'homologous series' of antibodies differing in combining site rigidity and cross-reactivity (with S. Smith-Gill of NIH), and the biophysical chemistry of aptamer/protein recognition (with A. Ellington of UT-Austin). A second main focus of the lab is the formulation of novel molecular diagnostics and sensors.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Research Consortia GCC Cluster NanoX GCC Cluster for Cellular and Molecular Biophysics Gulf Coast Cluster for Single Cell Omics  Appointments Title Department / School Institution Professor Biology and Biochemistry University of Houston

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