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Faculty Profile Last Modified Time: 10:56:14 AM Fri, 27 Mar 2020   Contact Information Michael Green Associated Profiles  Assistant Professor, Lymphoma/Myeloma Research, UT MD Anderson Cancer Center     mgreen5@mdanderson.org     (855)449-3933    Web Link    Lymphoma, Large B-Cell, Diffuse, Follicular Lymphoma, B-Lymphocytes, B-Cell Lymphoma, Neoplasms, Cells, Non-Hodgkin's Lymphoma, Lymphoma    Associated Profiles Professional Preparation Research and Expertise Affiliations Appointments  Professional Preparation  Degree Major Institution Year  PhD Molecular Genetics Griffith University 2009  BS Cell and Molecular Biology Victoria University of Wellington 2006  BS Human Genetics/Molecular Pathology Victoria University of Wellington 2005  Research and Expertise Research Interests   My research is focused on the molecular basis of B-cell lymphoma; a disease characterized by the arrested differentiation of B-cells that interact on multiple levels with the immune microenvironment. Specifically, I am interested in the intersection of genetics and immunology, and defining how the mutations in B-cell lymphoma perturb normal B-cell biology and alter interactions with non-malignant immune cells. My approach employs genomic screens and bioinformatics for the discovery of disease-specific or subtype-specific alterations that alter B-cell differentiation or immune interactions and have potential for therapeutic correction. I define the biological consequences of these alterations by integrating other profiles (e.g. gene expression profiles, or flow cytometry based proteomics) from the same tumor and/or investigating their effects using murine models or human cell lines. This has led to the discovery of therapeutically targetable genetic alterations that influence tumor immune interactions in classical Hodgkin's lymphoma, mediastinal large B-cell lymphoma and follicular lymphoma, and others that affect B-cell differentiation in diffuse large B-cell lymphoma and follicular lymphoma.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Research Consortia Gulf Coast Cluster for Single Cell Omics  Appointments Title Department / School Institution Assistant Professor Lymphoma/Myeloma Research UT MD Anderson Cancer Center

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