The tools of modern molecular biology allow the DNA of living organisms to be rapidly rewritten, and this in turn allows unnatural biological behaviors to be engineered. The Tabor lab takes a synthetic biological approach to studying how population-level phenomena, such as multicellular pattern formation and cooperation, are coordinated by the underlying gene regulatory networks. By constructing synthetic gene regulatory networks and linking cells together with artificial communication systems they aim to understand the rules by which a sequence of DNA can encode a population-level process. Also, by evolving their engineered gene circuits in the laboratory they can ask not only how biology works but why certain biological control systems are preferred over others. The study of biological 'design principles' has broad applications in science, medicine and biotechnology.
Publications/Creative Works
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