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Faculty Profile Last Modified Time: 11:55:48 AM Mon, 30 Mar 2020   Contact Information Xinli Liu Associated Profiles  Associate Professor, Pharmaceutics, University of Houston   Health 2, Room No.: 7048    xliu65@uh.edu     832-842-8390    Web Link    Molecularly Targeted Drug Delivery Systems, Nanoparticles, Nanoconjugates, Prodrugs, Anticancer Drugs, Cancer Metastasis, Nanotechnology, Chemical Synthesis, Cancer Biology, Imaging Methods    Associated Profiles Professional Preparation Research and Expertise Affiliations Appointments  Professional Preparation  Degree Major Institution Year  PhD   University of Kentucky 2004  BS   Lanzhou University 1999  Research and Expertise Research Interests   My research interest is to develop molecularly targeted drug delivery systems, such as nanoparticles, nanoconjugates and prodrugs, to improve tumor specific delivery of anticancer drugs and biologics to target cancer metastasis. My research uses pharmacokinetic and pharmacodynamic principles and employs multidisciplinary approaches, including nanotechnology, chemical synthesis, cancer biology, and imaging methods, to study the disposition and efficacy of the nanotherapeutics in preclinical cancer models. Currently, my research focuses on two main areas: 1) rational design and development of novel nanoparticles and nanoconjugates that can overcome various physiological and biological barriers (such as blood brain barrier), selectively accumulate at specific anatomical locations such as CNS and bone, efficiently target cancer metastasis, and eradicate tumor cells without harming normal cells; and 2) preclinical evaluations of novel anticancer drug combination and drug delivery systems that can overcome multidrug resistance.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Research Consortia GCC Cluster NanoX Gulf Coast Cluster for Translational Imaging Gulf Coast Cluster for Single Cell Omics  Appointments Title Department / School Institution Associate Professor Pharmacological & Pharmaceutical Sciences University of Houston

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