The long term objective of my research is to characterize the molecular evolution of organism and to reconstruct the evolutionary histories of genes and species. Approaches include (1) mathematical development of the theories of population genetics and evolution of DNA sequences; (2) development of statistical methods for analyzing molecular data and for reconstructing molecular phylogenies, especially the methods for testing important hypotheses about molecular evolution; (3) utilization of databases of the human genome as well as other organisms for comparative study, including functional analysis of DNA polymorphism; and (4) analysis of polymorphisms within individual cells.
Publications/Creative Works
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