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Faculty Profile Last Modified Time: 02:59:54 PM Fri, 15 Jan 2021   Contact Information Anjana Bhardwaj Associated Profiles  Assistant Professor, Breast Surgical Oncology, UT MD Anderson Cancer Center     abhardwaj@mdanderson.org     713-563-5045    Web Link    Breast Cancer, Prevention, Molecular Signatures, Atypia, Immune Environment, DCIS, Precancerous    Associated Profiles Professional Preparation Research and Expertise Affiliations Appointments  Professional Preparation  Degree Major Institution Year  PhD Cancer Biology Post Graduate Institute of Medical Education and Research 2002  MS Biophysics Panjab University 1997  BS Biophysics Panjab University 1994  Research and Expertise Research Interests   Dr. Bhardwaj's research interests involve understanding the early molecular changes that underlie the development of breast cancer and their targeting for prevention of breast cancer across all subtype including the most aggressive triple negative breast cancer for which there are no targeted therapies. Her research has been focused on identification of miRNA and their downstream functional genes changes that characterize pre-neoplastic transition in breast cancer and targeting of their downstream pathways for prevention of breast cancer by repurposing low toxicity drugs that are already in clinic. Her molecular profiling studies from breast samples that represent a histological continuum from normal to invasive breast cancer have revealed that a vast majority of gene and protein level changes occur early (during normal like to hyperplasia) transition in breast cancer development and suggest a changes in immune environment that might play a role in driving the progression of molecularly altered DCIS lesions to invasive breast cancer transition. These results have shaped her second line of her current research efforts that are focused on characterizing the immune environment during breast cancer development and if these can be targeted for prevention of breast cancer.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Research Consortia Gulf Coast Consortia Immunology Cluster Gulf Coast Cluster for Single Cell Omics Junior Faculty Network  Appointments Title Department / School Institution Assistant Professor Breast Surgical Oncology UT MD Anderson Cancer Center

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