Dr. Berry is a well known developer of statistical theory and methodology. He has designed and supervised the conduct of hundreds of innovative clinical trials, including Bayesian adaptive trials in cancer and other diseases. He has developed Bayesian adaptive designs that efficiently use information that accrues over the course of the trial. These trials minimize sample size while increasing the likelihood of detecting therapeutic activity. A principal focus of his research is the use of biomarkers for learning which patients benefit from which therapies, based on molecular markers and phenotype. In particular, he designed and is a co-PI of I-SPY 2 in high-risk early breast cancer, a trial that was the focus of the two lead articles with two editorials in the July 2016 NEJM. He has designed Phase 3 Bayesian adaptive platform clinical trials in glioblastoma, GBM-AGILE and pancreatic cancer.
Publications/Creative Works
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