The overall focus of the Membrane and Auditory Bioengineering Group is to understand and devise strategies to repair the auditory system. Through basic research into biological membranes and the intricate workings of the inner ear, the group is producing new insights into the causes of hearing loss and deafness. This research includes using cultured cells, 3D culture models, optical imaging, micromechanical manipulation and computational modeling to study the cellular and molecular basis of auditory function. Ultimately, the lab seeks to use the research knowledge to derive novel therapies for hearing loss and inspire new ideas for the design of biosensors and microscale biomedical devices. Ongoing projects include: Understanding the structure and function of prestin and its interaction with the membrane, Computational modeling of ion transport and homeostasis in the inner ear, Development of a 3D culture system of the inner ear, Development of methods to optically measure auditory nerve activity and stimulate the auditory nerve with next generation cochlear implants.
Publications/Creative Works
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Affiliations
Research Consortia
Gulf Cost Consortia for Theoretical & Computational Neuroscience
Training Grants
Houston Area Molecular Biophysics Training Program
NeuroEngineering IGERT
Center for NeuroEngineering
Training Grants
NLM Training Program in Biomedical Informatics & Data Science for Predoctoral and Postdoctoral Fellows
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