My research program aims at bringing a fundamental understanding of the biomolecular self-assembly that are implicated in oncogenic and neurodegenerative diseases. We are currently working on the biomolecular self-assembly that are predominantly disordered, such as liquid-like condensates; the biomolecular self-assembly that are regulated by disordered and heterogenous biomolecular targets including intrinsically disordered proteins and/or ribonucleic acids; the interplay between polymorphism, disordered intermediates and the underlying free energy surfaces; and the role of structural disorder in virulence factors that can evade immune system. The overarching goal of our research program is to improve human health by developing computational platforms that enable design of novel materials, pharmaceuticals, and diagnostic tools.
Publications/Creative Works
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Affiliations
Research Consortia
Gulf Coast Cluster for Cellular and Molecular Biophysics
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