Zhang, Ningyan (Faculty Profile)

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Faculty Profile

Last Modified Time: 05:05:05 PM Thu, 20 May 2021

Contact Information
Ningyan Zhang	Associated Profiles
Professor, Texas Therapeutics Institute, UT Health Science Center at Houston

Sarofim Research Building, Room No.: 537D
Ningyan.Zhang@uth.tmc.edu 713-500-3332 Web Link
Monoclonal Antibodies, Cancer Cells, Cell Culture, PCR, Protein Purification, Flow Cytometry, Cancer Biomarkers, Cloning, Electrophoresis, Western Blot Analysis

Professional Preparation
Research and Expertise
Affiliations
Appointments

Professional Preparation

Degree	Major	Institution	Year
PhD	Plant Biochemistry, Molecular Biology	University of Kentucky

Research and Expertise

Research Interests

The proteolytic process mediated by proteinases including matrix metalloproteinases (MMPs) in the tumor microenvironment plays a critical role in tumor growth, invasion, metastasis, and cancer drug resistance. The molecular mechanisms underlining the complex roles of proteinases in cancer biology are currently poorly understood. Recent studies suggest that proteinases in tumor microenvironment may invade host immunosurveillance by cleavage of antibodies or shedding cell surface receptors to allow cancer cells to escape immune response. Dr. Zhang will study the interactions between proteinases and anti-tumor antibodies in the tumor microenvironment to delineate the roles of proteinses play in tumor resistance to antibody immune therapies.

Publications/Creative Works

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Affiliations

Training Grants

The Cancer Therapeutics Training Program (CTTP)

Appointments

Title	Department / School	Institution
Professor	Texas Therapeutics Institute	UT Health Science Center at Houston

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