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Faculty Profile Last Modified Time: 10:54:00 AM Fri, 18 Jun 2021   Contact Information Robert Chapkin Associated Profiles  Professor, Biochemistry and Biophysics, Texas A&M University   Cater-Mattil, Room No.: 111    r-chapkin@tamu.edu     979-845-4426    Web Link    Lab Webpage    Biochemical Mechanisms of Marine and Plant Species-Derived Bioactive Agents: Role in Immune Modulation and Chemoprevention    Associated Profiles Professional Preparation Research and Expertise Affiliations Appointments  Professional Preparation  Degree Major Institution Year  PhD Nutrition and Physiological Chemistry University of California, Davis 1986  MSc Nutrition University of Guelph 1983  BSc Nutrition and Biochemistry University of Guelph 1981  Research and Expertise Research Interests   Research in the Chapkin lab focuses on dietary/microbial modulators related to the prevention of cancer and chronic inflammatory diseases. Our central goal is to (1) understand cancer chemoprevention at a fundamental level, and (2) to test pharmaceutical agents in combination with dietary/microbial (countermeasures to the Western diet) to more effectively improve gut health and reduce systemic chronic inflammation. Since diet influences gut microbiota composition and metabolite production, to unravel the interrelationships among gut health and the structure of the gut microbial ecosystem, we are in the process of evaluating (using transgenic mouse, Drosophila models and humans) how the gut microbiome modulates intestinal cells, innate immune cells and tumors. As part of this endeavor, we are modeling at the molecular level the dynamic relationship between diet and gut microbe-derived metabolites which modulate chronic inflammation and the hierarchical cellular organization of the intestine, e.g., stem cell niche.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Training Grants The Cancer Therapeutics Training Program (CTTP)  Appointments Title Department / School Institution Professor Biochemistry and Biophysics Texas A&M University

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