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Faculty Profile Last Modified Time: 02:00:46 PM Wed, 22 Apr 2020   Contact Information Pappanaicken R Kumar Associated Profiles  Assistant Professor, Lymphoma/Myeloma, UT MD Anderson Cancer Center     pkumaresan@mdanderson.org     713-792-2225    Web Link    Natural Killer Cells, Natural Killer Cell Receptors, T-Cells, T-Lymphocytes, Radioimmunotherapy, Cloning, Immunoconjugates, Chimeric Antigen Receptors    Associated Profiles Professional Preparation Research and Expertise Affiliations Appointments  Professional Preparation  Degree Major Institution Year  PhD Biochemistry The University of Madras 1994  M.Phil Biochemistry The University of Madras 1990  Research and Expertise Research Interests   Harnessing host immune system to fight against cancer has been my major research focus. I have developed small molecule immune-conjugates to treat CML disease. I was awarded "Hypothesis and exploration grant" from Department of defense to complete this study. At MD Anderson Cancer Center, we have developed a novel approach to restoring host immunity to fight invasive fungal infections by using pattern-recognition receptor Dectin-1 to redirect T-cell specificity against fungus. This work was published in "Proceedings of National Academy of Sciences" journal. I have received 5 year, R21/R33 grant to expand re-directed CAR T cell therapy approach to treat other invasive fungal infections such as Candidiasis and mucormycosis. I have published 31 original research articles and a book chapter in "Methods in Molecular biology" on "Proteases and Cancer". As a principal investigator, I have received 4 federal grants, 1 American cancer society grant, 1 Institutional research grant and 2 seed grant to conduct his research studies.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Research Consortia Junior Faculty Network  Appointments Title Department / School Institution Assistant Professor Lymphoma/Myeloma UT MD Anderson Cancer Center

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