My research is broadly aimed at understanding the mechanism by which the brain and immune system communicate. This includes an interest in understanding how psychological factors, such as stress, are able to impact our vulnerability to disease as well as how diseases, such as cancer, can impact how we feel, think, and behave.

Currently, the primary focus of my research is on understanding the mechanisms underlying cancer-related fatigue. There is growing evidence that the fatigue that develops in response to cancer and cancer therapy is likely a consequence of widespread inefficiency in cellular energy production. My research employs mouse models to better understanding these mechanisms. Further, the research within my laboratory aims to understand why a subset of individuals continue to experience debilitating fatigue and depression for months and even years after completion of cancer therapy. A multitude of variables (e.g., genetics, life experience, age, and disease/treatment-related factors) likely contribute to the risk of symptom persistence.