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Faculty Profile Last Modified Time: 01:42:12 PM Wed, 28 Mar 2018   Contact Information Victor Reyes Associated Profiles  Professor, Pediatrics, Microbiology & Immunology, UT Medical Branch at Galveston     vreyes@utmb.edu     (409) 772-3824    Web Link    Antigen Processing, T-Cell Presentation, Mucosal Immunity, Inflammatory Bowel Disease, Gastric Cancer, Peptic Ulcer Disease, Helicobacter Pylori, Stomach, Epithelial Cells, T-Lymphocytes, Helicobacter Infections, Peptides, Myofibroblasts    Associated Profiles Professional Preparation Research and Expertise Affiliations Appointments  Professional Preparation  Degree Major Institution Year  PhD Immunology University of Texas Medical Branch 1986  MS Medical Microbiology Texas Tech University, Medical Health Sciences Center 1982  BS Microbiology Texas Tech University 1980  Research and Expertise Research Interests   My group has made multiple contributions in mucosal immunology, including multiple contributions describing the immune response to Helicobacter pylori. Our group has characterized mucosal T cells and cytokine responses to the infection using multiplex arrays, such as those described in this application. We reported on the effects of H. pylori on the expression of B7 family members (aka immune checkpoint regulators) by the epithelium that impair local T cell responses, including the generation of T regulatory (Treg) cells. We have also characterized the expression on gastric epithelial cells and intestinal subepithelial myofibroblasts of proteins and features characteristic of antigen presenting cells and have shown how those cells may regulate the responses of CD4+ T cells as well as promote the expansion of Treg cells. In other recent studies, we have characterized the proteomic and cytokine response of the human gastric epithelium to Helicobacter pylori. Additional ongoing work is defining putative biomarkers of gastric cancer and peptic ulcer disease.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Research Consortia GCC Consortium for Antimicrobial Resistance (GCC AMR) Gulf Coast Consortia Immunology Cluster  Appointments Title Department / School Institution Professor Pediatrics UT Medical Branch at Galveston

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