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Faculty Profile Last Modified Time: 04:34:24 PM Wed, 18 Apr 2018   Contact Information Vladimir Motin Associated Profiles  Professor, Pathology, UT Medical Branch at Galveston     vlmotin@utmb.edu     (409) 772-3155    Web Link    Yersinia Pestis, Plague, Antigens, Yersinia Psuedotuberculosis, Yersinia, Plague Vaccine, Virulence, Genes    Associated Profiles Professional Preparation Research and Expertise Affiliations Appointments  Professional Preparation  Degree Major Institution Year  PhD Microbiology, Genetics Gamaleya Research Institute for Epidemiology and Microbiology 1988  BS Biophysics Institute for Engineering and Physics 1983  Research and Expertise Research Interests   Currently, my major research interest is the pathogenesis of Yersinia pestis, the etiological agent of plague. Although plague is not a public heath problem in most parts of the world, its potential for contagion, the lack of an effective vaccine, and the recent emergence of multiple antibiotic resistance strains place this organism squarely at the top of the United States' select agent list as a potential candidate for bioterrorism use. The long-term goal of my research is to elucidate the molecular mechanisms that underlie the nature of the acute bacterial infectious process caused by Y. pestis. The identification of the environmental signals that the bacteria encounter in the host cells and the potential virulence genes regulated by those signals will lead to a better understanding of the process of cross-talk between pathogen and its host during the infection. The unraveling of the Y. pestis virulence network will allow us to determine novel targets for therapeutics beyond antibiotics, to generate new vaccines and develop robust diagnostic assays.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Research Consortia GCC Consortium for Antimicrobial Resistance (GCC AMR)  Appointments Title Department / School Institution Professor Pathology UT Medical Branch at Galveston

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