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Faculty Profile Last Modified Time: 12:08:57 PM Mon, 23 Jul 2018   Contact Information Leng Han Associated Profiles  Assistant Professor, Biochemistry and Molecular Biology, UT Health Science Center at Houston   Medical School Building, Room No.: 6.166    Leng.Han@uth.tmc.edu     713-500-6039    Web Link    Lab Webpage    Cancer Genomics, Long Noncoding RNA, Neoplasms, CpG Islands, RNA Editing, Genome, Induced Pluripotent Stem Cells, Genes, MicroRNAs    Associated Profiles Professional Preparation Research and Expertise Affiliations Appointments  Professional Preparation  Degree Major Institution Year  PhD Bioinformatics & Genetics Chinese Academy of Sciences 2010  BS Biotechnology Wuhan University 2005  Research and Expertise Research Interests   Our research has included a diverse range of topics in bioinformatics and genomics. I use an integrative approach, combining comparative, computational, and functional genomic methods. Recent advances in genomic technologies and the ensuing deluge of genomic information related to cancer have accelerated the convergence of discovery science with clinical medicine. Successful translations of cancer genomics into therapeutics and diagnostics reinforce its potential for personalizing cancer medicine. As one of the most important cancer genomic data resources, The Cancer Genome Atlas (TCGA) is a comprehensive and coordinated effort to accelerate our understanding of the molecular basis of cancer through the application of genome analysis technologies. Besides, Large-scale exome sequencing data repositories, such as those of TCGA, the International Cancer Genome Consortium (ICGC), the 1000 Genomes Project, and the National Heart, Lung, and Blood Institute (NHLBI) Exome Sequencing Project, provide researchers with excellent secondary data-mining opportunities to study genomic data. Our research will focus on computational analysis from genomic sequences to other post-genomic data, including both DNA and RNA sequences, protein profiling, and epigenetic profiling, in an ongoing effort to find hidden treasures. We will have multiple projects, including: 1) Methodology driven projects, which will strengthen the students' bioinformatics/experimental skills; 2) Biological driven projects, which will strengthen the students' insight and understanding for biology and medicine; 3) Collaborative projects, which will strengthen students' communication skills.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Research Consortia Junior Faculty Network  Appointments Title Department / School Institution Assistant Professor Biochemistry and Molecular Biology UT Health Science Center Houston

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