With a rapidly growing aging population, society is facing a mounting challenge from aging-related neurodegenerative disorders, such as Alzheimer's, Parkinson's and Huntington's diseases. Our laboratory is interested in two questions that are important for these brain disorders: (1) what is the normal function of disease-causative genes?; (2) what regulates the formation of aggregates? We are using Drosophila, commonly known as the fruit fly and one of the best-studied genetic organisms, as a model system to address these questions. Currently our study focuses on Huntington's (HD) and Parkinson's diseases.
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