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Faculty Profile Last Modified Time: 09:40:56 AM Mon, 20 Sep 2021   Contact Information Fernanda Laezza Associated Profiles  Professor and Graduate Program Director, Pharmacology & Toxicology, UT Medical Branch at Galveston     felaezza@utmb.edu     409-772-9672    Web Link    Voltage-Gated Sodium Channels, Neurons, Glycogen Synthase Kinase 3, Neuronal Plasticity, Ion Channels, Proteins, Interneurons, Fibroblast Growth Factors    Associated Profiles Research and Expertise Affiliations Appointments  Research and Expertise Research Interests   The research in our laboratory is directed at understanding the cellular and molecular mechanisms underlying modulation of ion channels in relationship to intrinsic excitability, synaptic transmission and plasticity. Rapid progress in the complementary fields of molecular genetics and cellular electrophysiology has lead to the appreciation of mechanistic links between ion channel dysfunction, long-term alterations in neuronal activity and the phenotypic expression of a variety of neurological disorders. Hence, ion channels have become a promising and attractive target for drug discovery and for the development of new therapeutic treatments against human diseases. Our major effort is currently focused at understanding the physiological activity of the intracellular fibroblast growth factors (iFGFs), a set of four genes (FGF11-14) abundantly expressed in neurons of the central and peripheral nervous systems.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Research Consortia Gulf Coast Cluster for NeuroEngineering Gulf Coast Cluster for Translational Addiction Science GCC Mental Health Research Cluster  Training Grants Houston Area Molecular Biophysics Training Program  Appointments Title Department / School Institution Professor Pharmacology and Toxicology UT Medical Branch at Galveston

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