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Faculty Profile Last Modified Time: 09:32:35 AM Mon, 13 Apr 2020   Contact Information Therese Kosten Associated Profiles  Professor, Psychology, Director of Developmental, Cognitive, & Behavioral Neuroscience, Director of Developmental Behavioral Neuroscience Lab, University of Houston   Health and Biomedical Sciences, Room No.: 482    takosten@uh.edu     713-743-3724    Web Link    Learning and Memory, Behavioral Neuroscience, Neuropharmacology, Neuropsychopharmacology, Rats, Behavioral Pharmacology    Associated Profiles Research and Expertise Affiliations Appointments  Research and Expertise Research Interests   The overarching theme of our research program is to understand the contributions of genetic and environmental factors that influence and shape behavior via the involvement of the hypothalamic-pituitary-adrenal (HPA) axis and dopaminergic and noradrenergic systems. I study how behaviors reflective of substance use disorders (e.g., self-administration, conditioned place preference, etc) are affected by stress, sex, and early life manipulations. Indeed, we were one of the first laboratories to incorporate sex as a biological variable in our studies. Another aspect of my research is considered translational as it involves medication development. For example, we are constructing and testing vaccines for methamphetamine abuse and are identifying new pharmacological targets for alcoholism that we test using maintenance and reinstatement of operant responding for alcohol procedures. Broadly, my research program encompasses the areas of motivation, emotion, and learning with a focus on limbic regions, such as the nucleus accumbens and hippocampus, and the neuropharmacological and epigenetic changes that associate with these behaviors.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Research Consortia GCC Mental Health Research Cluster Gulf Coast Cluster for Translational Addiction Sciences Gulf Coast Consortium for Translational Pain Research GCC Cluster for Alcohol and Addiction Research  Appointments Title Department / School Institution Professor Psychology University of Houston

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