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Faculty Profile Last Modified Time: 03:05:22 PM Thu, 16 Apr 2020   Contact Information Kehe Ruan Associated Profiles  Professor, Medicinal Chemistry & Pharmacology, and Director, Center for Experimental Therapeutics and Pharmacoinformatics, University of Houston   Health Building 2, Room No.: 7039    khruan@uh.edu     713-743-1771    Web Link    Cancer Biology, Proteins, Biochemistry, Enzymes, NMR Spectroscopy, Receptors    Associated Profiles Research and Expertise Affiliations Appointments  Research and Expertise Research Interests   Signaling Molecules and Drugs: Eicosanoids, Non-steroidal anti-inflammatory drugs (NSAIDs), targeting eicosanoid-biosynthesizing drugs, targeting eicosanoid-signaling drugs. Therapeutics Development for Diseases: Using small compounds/peptide/protein/gene/cells to develop novel approaches targeting Vascular Diseases (such as stroke and heart diseases), cancers and tissue regenerations. Drug targets: G Protein coupling receptors, P450 enzymes, eicosanoid-synthesizing enzymes, eicosanoid receptors Molecular Mechanisms: Eicosanoid Biosynthesis and Signaling in thrombosis, ischemia, cancers and stem cells. Biomedical field: Protein engineering, peptide synthesis, drug designs, membrane proteins, NMR structural biology. Approaches: Molecular cloning, protein/cell engineering, cell engineering, animal models, NMR spectroscopy, high throughput screening, virtual screening, computational chemistry. Assay Development: Automation robotic system for High throughput drug screening, virtual drug designs and screening, integration of experimental and virtual approaches in drug designs and screening.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Research Consortia John S. Dunn GCC for Chemical Genomics John S. Dunn, Sr. GCC for Magnetic Resonance  Appointments Title Department / School Institution Professor Medicinal Chemistry & Pharmacology University of Houston

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