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Faculty Profile Last Modified Time: 01:58:47 PM Wed, 29 Mar 2023   Contact Information Stephen Wong Associated Profiles  Chair, Professor and Director, Shared Resources, Houston Methodist Cancer Center, and Director, TT & WF Chao Center for BRAIN     stwong@houstonmethodist.org     713-441-5883    Web Link    Intravital Microscopy, Systems Biology, Medical Imaging, Neuroimaging, Image Analysis, Cancer, Alzheimer's Disease, Medical Imaging Physics, Medical Informatics, Bioinformatics    Associated Profiles Research and Expertise Affiliations Appointments  Research and Expertise Research Interests   Dr. Wong's research focuses on understanding health and disease from a systems perspective in order to generate cost-effective strategies and solutions for disease management. His research approaches combine both experimental and high throughput biology with rigorous computational, bioinformatics, biophysics, and imaging methods to achieve a deep understanding of the functions of each component in biological systems and integration of them with multilevel systems analysis. For example, the consequences of genetic variation, cell-cell interactions and environmental factors are included to reflect the circumstances and microenvironments of the disease condition. Current research projects include pathway modeling and high throughput phenotyping approaches for target discovery and drug repurposing in combating neurological disorders and cancer, and for understanding the mechanisms of these diseases. Additional projects include reformulation of small molecule drugs using chemical biology approaches, the development of point-of-care molecular diagnosis and monitoring devices using biophotonics and nanotechnology techniques, and the development of label-free molecular image-guided cancer therapy platforms.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Research Consortia John S. Dunn GCC for Chemical Genomics  Training Grant Computational Cancer Biology Training Program  Appointments Title Department / School Institution Professor Computer Science and Bioengineering The Methodist Hospital Research Institute John S. Dunn, Sr. Presidential Distinguished Chair Biomedical Engineering The Methodist Hospital Research Institute

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