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Faculty Profile Last Modified Time: 10:52:08 AM Mon, 6 Apr 2020   Contact Information Kathryn Cunningham Associated Profiles  Chauncey Leake Distinguished Professor, Vice Chairman, Pharmacology and Toxicology, Director, Center for Addiction Research, UT Medical Branch at Galveston     kcunning@utmb.edu     (409) 772-9640    Web link    Cocaine, Serotonin, Receptor, Serotonin, 5-HT2C, Cues, Dopamine, N-Methyl-3,4-Methylenedioxyamphetamine, Nucleus Accumbens, Serotonin Receptors    Associated Profiles Research and Expertise Affiliations Appointments  Research and Expertise Research Interests   Dr. Cunningham and her team have made multiple contributions to our understanding of the neuropsychopharmacology of abused drugs and psychotherapeutics, the underlying neurobiology of behavior, and new target and drug discovery in neuropsychiatric conditions. With established strengths in pharmacology and neuroscience, Dr. Cunningham focuses on advancing the biological understanding of disorders with an addictive dimensionality (e.g., drug addiction, binge eating disorder, obesity) and developing effective and safe therapeutics to maximize human function. A primary focus is our cross-disciplinary, translational research efforts with medicinal and synthetic chemists, cell biologists, neuropharmacologists, and clinical scientists to pinpoint the critical roles of two serotonin proteins (5-HT2A and 5-HT2C receptors) in cocaine use disorder and the discovery of novel serotonergic medications to extend abstinence. Chemists and engineering collaborators Drs. Scott Gilbertson (University of Houston), Jai Rudra and Jia Zhou, work closely with Dr. Cunningham's laboratory on additional novel targets for therapeutics and neuroprobes. To facilitate this effort, we have established new cellular, behavioral and molecular screening tools to study these systems.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Research Consortia John S. Dunn GCC for Chemical Genomics Gulf Coast Cluster for Translational Addiction Science GCC Cluster for Alcohol and Addiction Research  Appointments Title Department / School Institution Chauncey Leake Distinguished Professor Pharmacology and Toxicology UT Medical Branch at Galveston

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