We are investigating how memories are encoded and retained in cells of our nervous system throughout an individual's lifetime. While we are concerned with determining how neurons communicate by sending chemical signals across synapses, we are even more interested in determining how such communication changes with experience — a process commonly referred to as synaptic plasticity. Identification of the mechanisms responsible for these changes will be significant in our attempts to understand the formation and storage of memories. We combine four lines of study to address mechanisms of synaptic plasticity and transmission in the mammailan CNS: biochemical and biophysical measurements, live-cell spectroscopy, three-dimensional reconstructions, and computational analyses.
Publications/Creative Works
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Affiliations
Research Consortia
Gulf Coast Consortium for Theoretical & Computational Neuroscience
Training Grants
Houston Area Molecular Biophysics Training Program
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