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Faculty Profile Last Modified Time: 11:41:45 AM Fri, 17 Apr 2020   Contact Information Peter Vekilov Associated Profiles  John and Rebecca Moores Professor, Professor, Chemical & Biomolecular Engineering and Chemistry, University of Houston   Engineering Bldg 1, Room No.: S233    vekilov@uh.edu     713-743-4315    Web Link    Lab Webpage    Protein Crystallization, Sickle-Cell Anemia, Nucleation, Phase Transitions in Protein Solutions, Protein Intermolecular Interactions, Phase Diagrams, Crystallization of Membrane Proteins, Kinetics and Stability of Crystal Growth, 3D Molecular Graphics    Associated Profiles Research and Expertise Appointments  Research and Expertise Research Interests   The primary focus of research in our group is phase transitions that occur in protein solutions. In the logical framework of our research efforts, the first building block is the study of the interactions between the protein molecules in solution. A second group of efforts aims at determinations of phase diagrams of solutions of different proteins, i.e., on the thermodynamics of phase transformations. As far as the kinetics of phase transitions is concerned, we investigate both the kinetics of generation of the new phase via nucleation or spinodal decomposition, and the processes of growth of the new phases. We have three nucleation projects: we investigate the nucleation of dense liquid droplets of the protein lysozyme and hemoglobin, and its transition into spinodal decomposition as the supersaturation is increased; we investigate the nucleation of the polymer fibers of the sickle cell hemoglobin that underlie the deadly sickle cell anemia, and we investigate the nucleation of protein crystals.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Appointments Title Department / School Institution Professor Chemical & Biomolecular Engineering University of Houston

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