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Faculty Profile Last Modified Time: 06:10:47 PM Thu, 17 Oct 2024   Contact Information Kenneth Hu Associated Profiles  Assistant Professor, Immunology, UT MD Anderson Cancer Center     khhu@mdanderson.org    Web Link    Lab Webpage   List of Publications    immunotherapy, tumor microenvironment, imaging, cell-cell communication, systems and spatial immunology    Associated Profiles Professional Preparation Research and Expertise Affiliations Appointments  Professional Preparation  Degree Major Institution Year  PhD Biophysics Stanford University 2017  BS Biology/Physics Massachusetts Institute of Technology 2012  Research and Expertise Research Interests   Our lab is broadly interested in identifying and perturbing the cell-cell interactions that lead to tissue organization, with a focus on tumor spatial heterogeneity and its role in immunotherapy response. The lab’s ultimate vision is to identify critical roadblocks to immunotherapy efficacy in solid tumors by examining how the spatial architecture of the tumor changes in response to immunotherapies. Much of my group is focused on technology development aimed at imaging tissue features and cellular functions that remain difficult to image in vivo, focusing on crosstalk between non-immune tumor stroma and the immune compartment. We then integrate this imaging data with cutting-edge spatial transcriptomics and proteomics to identify how tumor heterogeneity arises from cell-cell interactions and how this impacts the propagation of immunotherapy’s effects.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Research Consortia Gulf Coast Cluster for Single Cell Omics Gulf Coast Consortia Immunology Cluster  Appointments Title Department / School Institution Assistant Professor Immunology UT MD Anderson Cancer Center

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