University of Electronic Science and Technology of China
2012
Research and Expertise
Research Interests
Our research focuses on understanding how cancer initiates from early normal cells and evolves into complex clonal architectures and multicellular ecosystems. We seek to address this question by applying and developing cutting-edge genomics, single-cell multiomics and spatial genomics technologies. The overarching goal is to use the new knowledge from our research to facilitate the development of strategies for the prevention, detection and interception of cancer before it progresses to an intractable stage. Current research directions * Studying somatic mutations in normal and premalignant tissues and their impact on cancer development * Understanding premalignant progression and mutant clonal evolution * Resolving the microenvironment of premalignancy and cancer in space and time.
Publications/Creative Works
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