Our goal is to determine the role of inhibitory dysfunction in the pathogenesis of neurodevelopmental disorders by deciphering how genetic alterations perturb inhibition in the brain, impact neural development, and lead to abnormal neurologic output. In the Chao Lab, we integrate cross-species approaches in humans to uncover the genetic etiologies of neurodevelopmental disorders, fruit flies to elucidate the molecular pathways, and mice to explore the cascade of events in the mammalian brain. A wide variety of approaches and techniques are employed in our laboratory including genetically engineered mouse and fruit fly models, structural and functional analyses with electrophysiology, confocal and super-resolution imaging, transcriptomics, molecular and cellular assays, and comprehensive behavioral profiling.
Publications/Creative Works
Click here to search for this faculty member's publications on PubMed.
Affiliations
Research Consortia
Gulf Coast Consortium for Mental Health Research
Junior Faculty Network
Appointments
Title
Department / School
Institution
Assistant Professor
Molecular and Human Genetics, Neuroscience, Pediatrics-Neurology
Important Disclaimer: The responsibility for the accuracy of the information contained on these pages lies with the authors and user providing such information.