Synthetic Medicinal Chemistry, Small Molecule Drug Discovery, Antiviral Inhibitor Development, Enzyme Targets for Tuberculosis, Parasitic Diseases, Cysteine Proteases of Parasitic Protozoa and Coronavirus
Since 2014, the Meek lab's mission is to elucidate the chemical mechanisms of enzymes that are validated drug targets and to utilize these mechanisms to develop rationally-designed inhibitors and inactivators of these enzymes. We research the following diseases: tuberculosis, African sleeping sickness, Chagas disease, malaria, and COVID-19 utilizing synthetic and medicinal chemistry, protein expression, crystallography, molecular modeling, mechanistic enzymology, and inhibitor characterization.
Publications/Creative Works
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