Research in Dr. Nurieva's lab aims to elucidate the molecular basis of T cell mediated immune responses, and how abnormal immune regulation leads to immunodeficiency, autoimmunity, and cancer. In recent work, her lab showed that transplantation of Grail-deficient T cells into a mouse model of lymphoma was sufficient to inhibit the growth of established tumors, suggesting Grail is a potential target to improve the cancer immune response. Continuing studies will help us to understand the function of the immune system, and will, therefore, help develop approaches to design drugs against cancer, as well as against autoimmune disorders.
Publications/Creative Works
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