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Faculty Profile Last Modified Time: 03:07:32 PM Wed, 27 Jan 2021   Contact Information Ann Leen Associated Profiles  Professor, Pediatrics, Hematology-Oncology, Center for Cell and Gene Therapy, Baylor College of Medicine     aleen@bcm.edu    Web Link    Viral Immunology, Tumor Immunology, Virology, Pediatric Hematopoietic Stem Cell Transplantation, Cytotoxic T-Lymphocytes, Virus Diseases, T-Lymphocytes, Adoptive Transfer    Associated Profiles Professional Preparation Research and Expertise Affiliations Appointments  Professional Preparation  Degree Major Institution Year  PhD Immunology University of Birmingham 2002  BS Biochemistry University College Cork 1997  Research and Expertise Research Interests   Dr. Leen's research interests involve using cytotoxic T cells (CTL) for viral and malignant diseases. Dr. Leen is a co-principal investigator on a clinical trial assessing the safety of adoptively transferred donor-derived virus-specific CTL for the prophylaxis and treatment of adenoviral infections post allogeneic stem cell transplant. She is also developing and optimizing methods for generating tumor-specific CTL directed against the cancer testis antigens SSX2 and SSX4, which are expressed in a variety of tumors including Hodgkin Reed Sternberg cells. Therefore, the development of effective methods to reactivate and expand tumor-specific T cells directed against these antigens will lead to the development of immunotherapy protocols for the treatment of patients with relapsed EBV negative Hodgkin's disease and non-Hodgkin Lymphoma.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Research Consortia Gulf Coast Consortia Immunology Cluster  Training Grants The Cancer Therapeutics Training Program (CTTP)  Appointments Title Department / School Institution Professor Pediatrics, Hematology-Oncology, Center for Cell and Gene Therapy Baylor College of Medicine

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