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Faculty Profile Last Modified Time: 11:42:10 AM Mon, 6 Jul 2020   Contact Information Scott Evans Associated Profiles  Professor, Pulmonary Medicine, UT MD Anderson Cancer Center   Texas A&M Health Sciences Building, Room No.: 7.705    seevans@mdanderson.org     713-563-7433    Web Link    Lab Webpage    Pneumonia, Lung, Toll-Like Receptors, Alveolar Epithelial Cells, Infection, Pneumocystis, Glucans, Hematologic Neoplasms    Associated Profiles Professional Preparation Research and Expertise Affiliations Appointments  Professional Preparation  Degree Major Institution Year  MD Medicine The University of Texas Medical School 1999  BS Plan II The University of Texas 1994  Research and Expertise Research Interests   The entirety of my professional effort, both laboratory and clinical, is focused on the mechanisms that prevent humans from universally succumbing to the microbial pathogens they inhale or aspirate every day. In particular, I am interested in how non-HIV immunocompromised patients respond to the presence of respiratory pathogens. My goal is to exploit these native mechanisms to provide more comprehensive protection during episodes of peak vulnerability, such as when cancer patients receive chemotherapy. My laboratory is currently engaged full-time in mechanistic studies intended to unravel the means by which our recently described phenomenon of inducible resistance protects against pneumonia. Our available data indicate that this protective response occurs via antimicrobial product generation from treated respiratory epithelial cells, rather than through the typical leukocyte effectors of the innate immune system. My long term objective is to develop a research program focused on discovery and manipulation of epithelium-derived antimicrobial mediators that can ultimately be translated for clinical benefit.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Research Consortia Gulf Coast Consortia Immunology Cluster  Appointments Title Department / School Institution Professor Pulmonary Medicine UT MD Anderson Cancer Center

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