Dr. Melinda Yates is a laboratory investigator focusing on pharmacology and translational biology in gynecologic cancers. Her research emphasis is on understanding mechanisms of uterine and ovarian cancer development and using this knowledge to develop cancer prevention strategies for women at increased risk of cancer. This research focuses on hereditary cancer syndromes (Lynch syndrome-associated uterine cancer and Hereditary Breast Ovarian Cancer Syndrome), as well as cancers related to obesity and metabolic dysfunction. Dr. Yates also seeks to translate laboratory insights on genetic changes associated with uterine cancer development into clinical advances such as improved chemotherapeutic regimens and understanding (or predicting) a patient's response to therapy. Translational research in her laboratory spans across cell culture systems, genetically engineered mouse models, human tissue studies, and clinical trials.
Publications/Creative Works
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