Dr. Zuniga-Sanchez studied neuronal trafficking, and investigated how axons and dendrites acquire distinct morphologies during their development. She was awarded a Sally Cassanova pre-doctoral fellowship for her dedication and accomplishments, which allowed her work in the Laboratory of Professor Craig C. Garner at Stanford University. In Stanford, she researched a novel therapeutic method to treat cognitive impairments in the mouse model for Down's syndrome. The behavioral experiments that Elizabeth performed along with collaborators were published in 2007 in the journal of Nature Neuroscience (Fernandez et al., 2007). She continued researching neuronal development and began to investigate the signaling pathways involved in craniofacial development. She also discovered a new role of Jagged-Notch signaling. This revelation provided insights into the molecular mechanism behind craniofacial defects found in patients with Alagille syndrome, who also have mutations in the Jagged ligand and Notch receptor. In addition, she characterized the interactions of Notch with other known pathways such as Bmp and Endothelin signaling in forming distinct components of the face. Her work resulted in two first-author publications and a second-author publication in the journal of Development.
Publications/Creative Works
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