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Faculty Profile Last Modified Time: 08:47:12 AM Wed, 22 Apr 2020   Contact Information Sunhee Lee Associated Profiles  Associate Professor, Microbiology & Immunology, UT Medical Branch at Galveston   Truman Graves Blocker, Jr. Medical Research Building (MRB), Room No.: 3.142A    sunhlee@utmb.edu     (409) 772-5813    Web Link    Mycobacterium Bovis, Mycobacterium Tuberculosis, Vaccines, Mycobacterium Ulcerans, Mycobacterium, Buruli Ulcer, Mycobacterium Smegmatis, Gluconacetobacter    Associated Profiles Professional Preparation Research and Expertise Affiliations Appointments  Professional Preparation  Degree Major Institution Year  PhD Plant Pathology University of Arizona 2001  BS Biology Chinbuk National University 1993  Research and Expertise Research Interests   Dr. Lee's laboratory is currently studying the immune evasion strategies of Mycobacterium tuberculosis, the causative agent of tuberculosis. In particular, studies of mycobacterial modulation of host cell death mechanisms, as innate and adaptive immunity defense against intracellular pathogens, are main focuses of the laboratory. Using a M. tuberculosis transposon mutant library, they screened pro-cell death mutants of M. tuberculosis and found multiple genetic loci that are responsible for inhibiting infection-induced cell death of macrophages. The Lee lab studies these genes in relation to virulence and immunogenicity of pathogenic mycobacteria, which will provide the tools necessary to investigate the details of this host-pathogen interaction and provide new targets and approaches to develop therapeutics and vaccines for prevention of tuberculosis.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Training Grants Training Program in Antimicrobial Resistance (TPAMR)  Research Consortia Gulf Coast Consortia Immunology Cluster  Training Grants Antimicrobial Resistance Training Program in the Texas Medical Center (AMR-TPT)  Appointments Title Department / School Institution Associate Professor Microbiology & Immunology UT Medical Branch at Galveston

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