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Faculty Profile Last Modified Time: 12:01:22 PM Thu, 26 Mar 2020   Contact Information Benjamin Arenkiel Associated Profiles  Professor, Molecular and Human Genetics, Neuroscience, Developmental Biology, Baylor College of Medicine   Neurological Research Institute, Room No.: Suite 1170.12    arenkiel@bcm.edu     (713) 798-1960    Web Link    Lab Webpage    Molecular Biology, Genetics, Neuroscience, Genetic Engineering, Electrophysiology, Neuron, Stem Cells, Stem Cell Differentiation, Mouse Models, Circuit Analysis, Neuronal Differentiation, Recombinant DNA Technology, Embryonic Stem Cell, CLSM    Associated Profiles Professional Preparation Research and Expertise Affiliations Appointments  Professional Preparation  Degree Major Institution Year  PhD Genetics University of Utah School of Medicine 2004  BS Microbiology, Chemistry St. Cloud State University 1998  Research and Expertise Research Interests   The main focus of our research is to elucidate the basic mechanisms that guide the formation and maintenance of neural circuits in the mammalian brain. Using the mouse, we apply multifaceted experimental approaches that combine genetic engineering, optical imaging, and electrophysiological recording techniques to better understand synapse and circuit function. The blueprints for most neural circuits are specified by innate, genetic mechanisms. However, circuit architecture and function can be strongly influenced by neural activity and sensory experience. Towards better understanding the interplay between experience, synaptic connectivity, and circuit function, we are currently pursuing three main projects in our laboratory: 1) Identifying activity dependent- and neuropeptide signaling mechanisms that underlie synaptogenesis and circuit formation of adult-born neurons. 2) Mapping functional connectivity of brain circuits, with emphasis on the olfactory system, basal forebrain, and hypothalamus. 3) Elucidating signaling and circuit mechanisms that govern feeding behavior. The long-term goal of our research is to form a deeper understanding of the mechanisms that guide synapse and circuit formation, with the ultimate hope of gaining insight towards repairing or replacing damaged or diseased nervous tissue. At the heart of this experimentation is the continued effort to develop novel tools and techniques to mark and manipulate neurons and their associated circuits.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Research Consortia Gulf Coast Cluster for Translational Imaging  Appointments Title Department / School Institution Associate Professor Molecular and Human Genetics, Neuroscience, Developmental Biology Baylor College of Medicine

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