Our laboratory works at the intersection of three fields: epigenetics, top down proteomics and cancer. We use cutting edge top down proteomics tools to study the proteoforms of histones, transcription factors, nuclear receptors, co-activators/co-repressors, and chromatin 'readers', 'writers' and 'erasers'. This proteoform level analysis of chromatin provides new insights into how chromatin regulatory mechanisms work and inform potential therapeutic strategies for cancer.
Publications/Creative Works
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Affiliations
Research Consortia
GCC Cluster for Cellular and Molecular Biophysics
Training Grants
Houston Area Molecular Biophysics Training Program
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