The Pfaffinger lab focuses on understanding the regulation of ion channels and their roles in native neurons. He has made important contributions to our understanding of ion channel regulation by G-protein coupled receptors, the assembly and trafficking of ion channels, and the mechanisms by which auxiliary subunit proteins are involved in driving diverse functional expression of ion channels from a relatively small number of genes. Currently, research in his lab is focusing on understanding the roles of channel diversity in information processing as well as the biophysical mechanisms underlying ion channel regulation by small peptide modulators and the role of this regulation in the brain.
Publications/Creative Works
Click here to search for this faculty member's publications on PubMed.
Important Disclaimer: The responsibility for the accuracy of the information contained on these pages lies with the authors and user providing such information.