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Faculty Profile Last Modified Time: 01:40:27 PM Mon, 20 Apr 2020   Contact Information Venugopal Reddy Venna Associated Profiles  Assistant Professor, Neurology, UT Health Science Center at Houston   MSE R342    Venugopal.R.Venna@uth.tmc.edu     713-500-7037    Web Link    Stroke, Social Isolation, Brain Ischemia, Middle Cerebral Artery Infarction, Brain-Derived Neurotrophic Factor, Adenosine Monophosphate, Protein Kinases, Metformin    Associated Profiles Professional Preparation Research and Expertise Appointments  Professional Preparation  Degree Major Institution Year  PhD   University of Lille-2 2009  BS   Gulbarga University    Research and Expertise Research Interests   Dr. Venna is currently working on several translational research projects in the field of ischemic stroke. His work primarily focuses on the identification and development of novel therapeutic approaches to improve ischemic stroke outcomes by reducing neuronal death and enhancing post-stroke recovery. In line with his previous behavioral research interests, Dr. Venna utilizes a variety of experimental models to explore the mechanisms underlying post-stroke depression and cognitive impairment. One of Dr. Venna's current projects examines the role macrophage migration inhibitory factor (MIF) in post-stroke outcome in young and aged animals. MIF is a cytokine that plays a key role in inflammation and innate immune signaling in both central and peripheral tissue. Importantly, MIF has recently been identified as a major contributor to depression. Although it is well accepted that depression contributes to impaired recovery after stroke, it remains unclear whether MIF signaling contributes to post-stroke depression and recovery. Dr. Venna is currently performing detailed and translationally relevant studies to elucidate the role of MIF signaling on depression and functional recovery after ischemic stroke. This project will help us better understand the underlying mechanisms involved in post-stroke recovery, facilitate the identification of reliable biomarkers of stroke recovery and serve as the basis for the development of future therapeutics for use in stroke patients.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Appointments Title Department / School Institution Assistant Professor Neurology UT Health Science Center at Houston

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