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Faculty Profile Last Modified Time: 01:37:00 PM Mon, 20 Apr 2020   Contact Information Randa El-Zein Associated Profiles  Professor, Radiology, Houston Methodist Research Institute     rel-zein2@houstonmethodist.org    Web Link    Lung Cancer, Breast Cancer, Radiogenomics, Genetic Susceptibility, Lung Neoplasms, Inflammatory Breast Neoplasms, Glioma, Genes, Neoplasms, Lymphocytes, Cytokinesis, DNA Repair, Micronucleus Tests, Chromosome Aberrations    Associated Profiles Professional Preparation Research and Expertise Appointments  Professional Preparation  Degree Major Institution Year  PhD   UT Medical Branch at Galveston    MS   Alexandria University    MBBCh   Alexandria University    Research and Expertise Research Interests   Dr. El-Zein's research focus is on understanding the role of gene-environment interactions in the risk of cancer development. She has developed expertise in the area of biomarkers and genetic susceptibility to disease. She has applied unique markers to identify several inherited genetic traits that influence human sensitivity to different cancers such as lung, breast and lymphomas. Dr. El-Zein's laboratory has a translational research approach, and is currently studying human populations using quantitative imaging coupled with molecular biomarkers to identify unique signatures that would improve the power of cancer risk assessment models. The results from these studies are providing new information that has significant and practical public health implications in the area of early detection and primary prevention of disease. The overall goal is to develop novel approaches to identify susceptible individuals at high risk of developing lung and breast cancers. New knowledge generated from these research endeavors are geared to fulfill the need for rapid and efficient translation of emerging new technologies and approaches for improved patient management, early detection and prevention.Dr. El-Zein's research focus is on understanding the role of gene-environment interactions in the risk of cancer development. She has developed expertise in the area of genotypic and phenotypic biomarkers and genetic susceptibility to disease. She has applied these unique markers to identify several inherited genetic traits that influence human sensitivity to different cancers such as lung, breast and lymphomas. Dr. El-Zein's laboratory has a translational research approach, and is currently studying human populations using quantitative imaging coupled with molecular biomarkers to identify unique signatures that would improve the power of cancer risk assessment models. The results from these studies are providing new information that has significant and practical public health implications in the area of early detection and primary prevention of disease. The overall goal is to develop novel approaches to identify susceptible individuals at high risk of developing lung and breast cancers. New knowledge generated from these research endeavors are geared to fulfill the need for rapid and efficient translation of emerging new technologies and approaches for improved patient management, early detection and prevention.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Appointments Title Department / School Institution Professor Radiology The Methodist Hospital Research Institute

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