The overarching goal of my laboratory is to understand the molecular mechanisms of breast tumor progression and metastasis. Our major interests include regulatory RNAs and deubiquitinating enzymes. We have played a major role in establishing the current models of non-coding RNA regulation of epithelial-mesenchymal transition, metastasis, and therapy resistance. Moreover, we discovered the deubiquitinases for key cancer proteins; some of these deubiquitinases are promising therapeutic targets.
Publications/Creative Works
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