Dr. McCrea is a Professor in the Department of Genetics. His laboratory seeks to reveal the biology of varied catenin proteins in primary cell/ cell line settings as well as in vivo, with the latter involving amphibian embryos to ease the viewing and manipulation of all vertebrate embryonic stages. The group's research spans the roles of catenins in nuclear gene control ( e.g. via Wnt-pathway modulation), their involvement in cytoskeletal control ( e.g. via small-GTPases), and their interactions with novel entities or cell junctional complexes ( e.g. cadherin-catenin functions). The lab's long-range purpose is to understand how the roles of catenins are networked in normal development and disease states such as cancer.
Publications/Creative Works
Click here to search for this faculty member's publications on PubMed.
Important Disclaimer: The responsibility for the accuracy of the information contained on these pages lies with the authors and user providing such information.