Javascript must be enabled to use this form.

View Profile	Home Browse Faculty Facility Research Consortia Training Grants Courses Search Support About rSp Help and FAQ's Contact Us	GCC Home
Faculty Profile Last Modified Time: 08:50:01 AM Mon, 30 Mar 2020   Contact Information Bhupendra Singh Kaphalia Associated Profiles  Professor, Pathology, UT Medical Branch at Galveston, Director, Analytical Chemistry Core, UT Medical Branch at Galveston     bkaphali@utmb.edu     409.772.4995    Web Link    Fatty Acids Liver Ethanol Poisons Esters Pesticide Residues Peromyscus Alcohol Dehydrogenase Anilides Trichloroethylene DDT Lindane Oils Lipids Autoimmunity Proteins Alcohols Pancreas Hep G2 Cells Acin    Associated Profiles Research and Expertise Affiliations Appointments  Research and Expertise Research Interests   The overall objective of my research program is to understand metabolic basis and mechanism of alcoholic pancreatitis. Since chronic alcohol abuse impairs hepatic alcohol dehydrogenase (ADH, major enzyme responsible for ethanol oxidation), we are using hepatic ADH deficient (ADH-) deer mice to understand the metabolic basis and mechanism of alcoholic pancreatitis. Currently, I am working in AMPK signaling and lipid metabolomics, including the analysis of oxidative and nonoxidative metabolites of ethanol in the pancreas and plasma of ethanol-fed hepatic ADH-deer mice and in isolated human pancreatic acinar cells exposed to ethanol to understand the etiopathogenesis of alcoholic pancreatitis, and identify biomarker(s) and therapeutic target(s).  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Research Consortia GCC Cluster for Alcohol and Addiction Research  Appointments Title Department / School Institution Professor Pathology UT Medical Branch at Galveston

powering - The Partnership
Important Disclaimer: The responsibility for the accuracy of the information contained on these pages lies with the authors and user providing such information.