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Faculty Profile Last Modified Time: 12:42:21 PM Mon, 18 Jul 2022   Contact Information Jonathan Hommel Associated Profiles  Associate Professor, Pharmacology & Toxicology, UT Medical Branch at Galveston     jonathan.hommel@utmb.edu     409-747-7057     409-747-7050    Web Link    Hommel Laboratory   Translational Research Scholars Program    Nucleus Accumbens Nicotinamide N-Methyltransferase High Fat Diet Food Feeding Behavior Paraventricular Hypothalamic Nucleus Obesity Cocaine Fats Origin Recognition Complex RNA Interference Leptin Mesencephalon Neurope    Associated Profiles Professional Preparation Research and Expertise Affiliations Appointments  Professional Preparation  Degree Major Institution Year  PhD Integrative Biology UT Southwestern Medical School 2005  BS Genetics Texas A&M University 2000  Research and Expertise Research Interests   Obesity and eating disorders are a major public health problem and key contributors to the burden of chronic disease in the United States and worldwide. These disorders are mediated by complex behavioral and metabolic components, each providing opportunity for prevention and treatment. To this end, we are focusing on the CNS circuits that regulate food addiction and motivation for energy-dense foods. In particular, we are interested in how neuropeptides, such as Neuromedin U, modulate neurons and impact food craving, food reward, and food preference. To study these problems, we use an array of techniques including viral-mediated gene knockdown, immunohistochemistry, neuronal tracing, and fluorescent in situ hybridization in multiple animal models of eating behavior and obesity. We then develop novel pharmaceutical therapeutics based on this new understanding of the mechanisms of eating behavior.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Research Consortia GCC Mental Health Research Cluster GCC Cluster for Alcohol and Addiction Research  Appointments Title Department / School Institution Assistant Professor Pharmacology & Toxicology UT Medical Branch at Galveston

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