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Faculty Profile Last Modified Time: 08:39:23 AM Mon, 30 Mar 2020   Contact Information Greg Cuny Associated Profiles  Associate Professor, Pharmacological & Pharmaceutical Sciences, University of Houston     4849 Calhoun Road, Houston, TX 77204-5037     Health Building 2, University of Houston College of Pharmacy, Room No.: 7036    gdcuny@uh.edu     713-743-1274    Web Link    Associated Profiles Professional Preparation Research and Expertise Affiliations Appointments  Professional Preparation  Degree Major Institution Year  PhD Organic Chemistry Massachusetts Institute of Technology    Research and Expertise Research Interests   The research interest of our lab is in the field of medicinal chemistry. The primary goal of our research is to develop in vivo pharmacology probes to study novel therapeutic approaches to treat diseases. Currently, we are studying several classes of alkaloids and disulfide containing cyclic peptides. The natural and non-natural products generated are then screened for biological activity in assays related to various therapeutic areas. The lab is also involved in several collaborative projects related to pharmacological probe development. One of these projects aims to design selective inhibitors of inosine-5'-monophosphate dehydrogenase (IMPDH) from the protozoan parasites Cryptosporidium parvum, which are potential bio-warfare agents and major causes of diarrhea and malnutrition. This project also has expanded to include other microorganisms that may be susceptible to selective IMPDH inhibition. Another project aims to design subtype selective inhibitors of activin-like kinase 2 (ALK2). This target has been implicated in a variety of diseases, including bone and cardiovascular diseases. Finally, another project aims to design selective inhibitors receptor interacting kinase 2 and 3 (RIPK2 and RIPK3), which may be involved in a variety of acute and chronic conditions, including inflammatory diseases.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Research Consortia Alcohol and Addiction Research  Appointments Title Department / School Institution Associate Professor Pharmacological & Pharmaceutical Sciences University of Houston

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