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Faculty Profile Last Modified Time: 10:32:02 AM Tue, 31 Mar 2020   Contact Information Melvin Klegerman Associated Profiles  Professor, Cardiovascular Medicine, UT Health Science Center at Houston   BBSB 5318    melvin.e.klegerman@uth.tmc.edu     713.486.2343    Web Link    Immunochemistry, Immunoassay Development, Conjugation Chemistry, Targeted Immunoliposomes for Diagnosis and Treatment of Cardiovascular Diseases    Associated Profiles Professional Preparation Research and Expertise Affiliations Appointments  Professional Preparation  Degree Major Institution Year  PhD Biochemistry Loyola University Chicago 1984  BA Chemistry University of Illinois, Chicago 1968  Research and Expertise Research Interests   The molecular targeting program of the cardiology research laboratories is focused on liposomal (and other particulate) targeting strategies aimed at developing improved modalities for diagnosis and treatment of cardiovascular and other diseases; molecular aspects of protein-lipid interactions; energetics of non-covalent interactions; molecular strategies for ultrasound imaging enhancement; biochemical, cellular and immunologic mechanisms of atherogenesis; immunochemical and biochemical assay development; and mechanisms of thrombosis and thrombolysis. Cardiology research wet lab facilities on the 5th floor of the new Behavioral and Biomedical Sciences Building (BBSB) on the south campus currently include access to a cell culture module, clinical and research ultrasound instrumentation, animal catheterization laboratory, large animal micro CT, a near infrared fluorescent imaging system, a UV/VIS spectrophotometer, lyophilizers, liquid chromatography and electrophoresis instrumentation, light microscopes, sonicators, table-top and high-speed centrifuges, flow cytometers, microplate readers, fluorescence microscopes and an ultracentrifuge. Our animal research protocols are performed in state-of-the-art facilities on the 6th floor of BBSB, in the adjacent CABIR building and in the Medical School Extension. Computer resources are focused on biomedical engineering applications with an emphasis on imaging algorithms.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Research Consortia GCC Cluster NanoX  Appointments Title Department / School Institution Professor Cardiovascular Medicine UT Health Science Center at Houston

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