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Faculty Profile Last Modified Time: 11:25:06 AM Mon, 30 Mar 2020   Contact Information Ali Azhdarinia Associated Profiles  Associate Professor, Center for Molecular Imaging, UT Health Science Center at Houston   South Campus Research Building 3, Room No.: 6.4680    Ali.Azhdarinia@uth.tmc.edu     713.500.3577    Web Link    Targeted Agents, Visualization and Treatment of Disease, Contrast Agents, Radioactive and Near-Infrared Fluorescent Labels, Whole-Body and Intraoperative Imaging, Molecular Targeting Strategies    Associated Profiles Professional Preparation Research and Expertise Affiliations Appointments  Professional Preparation  Degree Major Institution Year  PhD   The University of Texas Health Science Center at Houston 2005  Research and Expertise Research Interests   At UTHSC, Dr. Azhdarinia is the faculty lead of the Radio- and Optical-Pharmaceutical development effort in the Center for Molecular Imaging (CMI). His research interests include the development of targeted agents for the visualization and treatment of cancer. Dr. Azhdarinia has served as the leader of the National Cancer Network's Network for Translational Research (NTR) Chemistry Core and is heavily involved in validation and qualification of preclinical studies prior to translation in both NTR-wide and CMI local studies. His work utilizes radioactive and near-infrared fluorescent (NIRF) contrast agents which can be used for whole-body and intraoperative imaging, respectively, and may potentially improve surgical outcome while minimizing morbidities associated with current methods. The combination of both modalities into a single agent is a key area where Dr. Azhdarinia has focused his efforts through synthesis of a library of new multimodal chelation (MMC) platforms. The Azhdarinia Lab uses radiometal-based positron emitters, such as Gallium-68 and Copper-64, for labeling of peptides, proteins, and antibody-based agents. His lab also conducts full pharmacological characterization of lead compounds to determine suitability for clinical translation. As part of the Center for Molecular Imaging, Dr. Azhdarinia has participated in establishing a dedicated clean room for production of probes under Current Good Manufacturing Practices (cGMP) to facilitate translational research. The Azhdarinia Lab is actively collaborating with clinical partners to establish creative approaches for translating "dual-labeled" agents.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Research Consortia GCC Cluster NanoX  Appointments Title Department / School Institution Associate Professor Center for Molecular Imaging UT Health Science Center at Houston

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