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Faculty Profile Last Modified Time: 02:42:32 PM Fri, 27 Mar 2020   Contact Information Jason Eriksen Associated Profiles  Associate Professor, Pharmacology, University of Houston   Health 2    jeriksen@central.uh.edu     713-743-1226    Web Link    Cell Culture, Molecular Cloning, Neuroscience, Neurobiology, Neurodegenerative Diseases, Neurodegeneration, Catalysis, Alzheimer's Disease, Neuroprotection, Neuron, Gerontology    Associated Profiles Professional Preparation Research and Expertise Affiliations Appointments  Professional Preparation  Degree Major Institution Year  PhD Neuroscience Loyola University Chicago 2000  BS Biology & English Wake Forest University 1994  Research and Expertise Research Interests   Many neurodegenerative diseases, including Huntington's, Parkinson's, and Alzheimer's diseases, in human patients are both poorly understood and untreatable. In order to develop a deeper understanding of these disorders, a unifying theme in our lab is the study of mechanisms by which protein misfolding in the central nervous system leads to severe brain degeneration. Our research suggests that the manipulation of protein quality control systems, including the ubiquitin-proteasome system, the autophagic pathway, and heat-shock proteins may all exert dramatic effects on the development of pathology in these diseases. We use a variety of approaches, ranging from simple biochemical assays to complex transgenic organisms, in order to better understand the specific molecular and biochemical pathways that are involved in these diseases.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Research Consortia GCC Cluster NanoX GCC Cluster for Cellular and Molecular Biophysics  Appointments Title Department / School Institution Associate Professor Pharmacology University of Houston

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