Our ultimate research goal is to describe how large dynamic macromolecular complexes (biological nanomachines) work in quantitative terms. Understanding the structure of these machines in atomic detail is key to achieving this goal. We use a combination of X-ray crystallography and electron microscopy with other biochemical and biophysical techniques. The following systems are of interest from the basic, fundamental science side or because of their importance in technological or medicinal applications.
Publications/Creative Works
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Affiliations
Training Grants
Computational Cancer Biology Training Program
Research Consortia
GCC Cluster for Cellular and Molecular Biophysics
Training Grants
Houston Area Molecular Biophysics Training Program
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