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Faculty Profile Last Modified Time: 09:51:57 AM Mon, 23 Jul 2018   Contact Information Assaf Gottlieb Associated Profiles  Assistant Professor, Center for Precision Health, School of Biomedical Informatics, UT Health Science Center at Houston   University Center Tower, Room No.: 820    Assaf.Gottlieb@uth.tmc.edu     713-500-3698     713-500-3912    Web Link    Gene Expression, Drugs, Genes, Pharmaceutical Preparations, Gene Expression, Gene, Filtering, Crowdsourcing, Electronic Health Records, Precision Medicine, Entropy, Telomere Homeostasis, Amino Acyl-TRNA Synthetases, Systems Biology    Associated Profiles Professional Preparation Research and Expertise Affiliations Appointments  Professional Preparation  Degree Major Institution Year  PhD Computational Biology Tel Aviv University 2010  MSc Physics Tel Aviv University 2001  BSc Physics and Computer Science Tel Aviv University 1998  Research and Expertise Research Interests   Dr. Gottlieb's lab is interested in understanding and modeling drugs mode of action and their relation to drug efficacy, adverse reaction and pharmacogenomics. His lab employs an integrative computational approach, combining multiple types of data and applying methodologies from systems medicine, machine learning and causal inference domains to identify population and patient-level factors associated with drug efficacy and adverse reactions and to suggest candidates for drug repurposing. Additionally, his research leverages electronic health records for hypothesis generation and validation of therapeutic outcomes. Our lab is currently involved in interesting projects beyond therapeutics. The first project predicting gene expression from genomic polymorphism. Another project involves collaboration with the Department of Pediatric Surgery, studying traumatic brain injury. Last, we have projects in initial phases in detecting genomic locations associated with coronary artery disease and Alzheimer's disease.  Publications/Creative Works Click here to search for this faculty member's publications on PubMed.  Affiliations  Training Grants NLM Training Program in Biomedical Informatics & Data Science for Predoctoral and Postdoctoral Fellows  Appointments Title Department / School Institution Assistant Professor Biomedical Informatics UT Health Science Center Houston

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